Methemoglobin (SpMet®)

Methemoglobin (SpMet®)

Masimo is passionate about making innovative technologies that give clinicians the tools they need to do what is best for patient care. That's why it is gratifying to see so many clinicians and clinical researchers take the time to evaluate our products and technologies.

 

Click on the links below to read featured studies for Masimo’s technologies, or in the sections below for access by subject area to all studies.

Clinical Evidence

Methemoglobinemia after Liposuction under Tumescent Local Anaesthesia – Diagnostic Value of Pulse Oximetry

Brandt S, Kimberger O, Weber B, Klose A, Stockmann S, Schmeller W, et al . WJPS. 2022; 11 (1) :111-116. doi: 10.52547/wjps.11.1.111.

Methemoglobin and nitric oxide therapy in Ugandan children hospitalized for febrile illness: results from a prospective cohort study and randomized double-blind placebo-controlled trial.

Conroy AL, Hawkes M, Hayford K, Hermann L, McDonald CR, Sharma S, Namasopo S, Opoka RO, John CC, Liles WC, Miller C, Kain KC. BMC Pediatr. 2016 Nov 4;16(1):177.

Pulse-Oximetric Measurement of Prilocaine-Induced Methemoglobinemia in Regional Anesthesia.

Soeding P., Deppe M., Gehring H. Anesth Analg. 2010 Oct;111(4):1065-8.

Severe Methemoglobinemia Detected by Pulse Oximetry.

Annabi E.H., Barker S,J. Anesth Analg. 2009;108:898–9.

Improved Accuracy of Methemoglobin Detection by Pulse CO-Oximetry during Hypoxia.

Feiner J.R., Bickler P.E. Anesth Analg. 2010 Nov;111(5):1160-7.

The Measurement of Carboxyhemoglobin and Methemoglobin using a Non-Invasive Pulse CO-Oximeter.

Zaouter C., Zavorsky G.S. Respir Physiol Neurobiol. 2012 May 15;182(2-3):88-92.

Non-Invasive Measurements of Carboxyhemoglobin and Methemoglobin in Children with Sickle Cell Disease.

Caboot J.B., Jawad A.F., McDonough J.M., Bowdre C.Y., Arens R., Marcus C.L., Mason T.B., Smith-Whitley K., Ohene-Frempong K., Allen J.L. Pediatr Pulmonol. 2012 Aug;47(8):808-15.

Measurement of Carboxyhemoglobin and Methemoglobin by Pulse Oximetry: A Human Volunteer Study.

Barker S.J., Curry J., Redford D., Morgan S. Anesthesiology. 2006 Nov;105(5):892-7.

Methemoglobinemia after Liposuction under Tumescent Local Anaesthesia – Diagnostic Value of Pulse Oximetry

Brandt S, Kimberger O, Weber B, Klose A, Stockmann S, Schmeller W, et al . WJPS. 2022; 11 (1) :111-116. doi: 10.52547/wjps.11.1.111.

Methemoglobin and nitric oxide therapy in Ugandan children hospitalized for febrile illness: results from a prospective cohort study and randomized double-blind placebo-controlled trial.

Conroy AL, Hawkes M, Hayford K, Hermann L, McDonald CR, Sharma S, Namasopo S, Opoka RO, John CC, Liles WC, Miller C, Kain KC. BMC Pediatr. 2016 Nov 4;16(1):177.

Pulse CO-Oximetry - Clinical Impact in the Emergency Department

Exadaktylos A, Braun CT, Ziaka M, Trends in Anaesthesia and Critical Care (2014), doi: 10.1016 j.tacc.2014.07.002.

Methemoglobinemia Precipitated by Benzocaine Used During Intubation

Afzal A, Collazo R, Fenves AZ, Schwartz J. Proc (Bayl Univ Med Cent). 2014 Apr;27(2):133-5.

Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Prilocaine versus Lidocaine.

Gutenberg L.L., Chen J.W., Trapp L.. Anesth Prog. 2013 Fall;60(3):99-108.

Non-Invasive Measurements of Carboxyhemoglobin and Methemoglobin in Children with Sickle Cell Disease.

Caboot J.B., Jawad A.F., McDonough J.M., Bowdre C.Y., Arens R., Marcus C.L., Mason T.B., Smith-Whitley K., Ohene-Frempong K., Allen J.L. Pediatr Pulmonol. 2012 Aug;47(8):808-15.

The Measurement of Carboxyhemoglobin and Methemoglobin using a Non-Invasive Pulse CO-Oximeter.

Zaouter C., Zavorsky G.S. Respir Physiol Neurobiol. 2012 May 15;182(2-3):88-92.

The current status of continuous noninvasive measurement of total, carboxy, and methemoglobin concentration.

Shamir M.Y., Avramovich A., Smaka T. Anesth Analg. 2012 May;114(5):972-8.

Improved Accuracy of Methemoglobin Detection by Pulse CO-Oximetry during Hypoxia.

Feiner J.R., Bickler P.E. Anesth Analg. 2010 Nov;111(5):1160-7.

Pulse-Oximetric Measurement of Prilocaine-Induced Methemoglobinemia in Regional Anesthesia.

Soeding P., Deppe M., Gehring H. Anesth Analg. 2010 Oct;111(4):1065-8.

Accuracy of Methemoglobin Detection by Pulse CO-Oximetry during Hypoxia.

Feiner J.R., Bickler P.E., Mannheimer P.D. Anesth Analg. 2010 Jul;111(1):143-8.

Pulse Oximeter Methemoglobin Measurements in Patients with Tumescent Anaesthesia and Prilocaine.

Boye S., Opp A., Klose A., Schmeller W., Gehring H. Proceedings of the 2010 Annual Meeting of the American Society of Anesthesiologists. A886.

The Usefulness of Noninvasive MetHb Monitoring at HBOT Department (Pulse CO-Oximetry Masimo Rainbow SET RAD-57).

Nakashima M., Tsutsumi Y., Ifuku T., Tachibana H., Tamehiro K. , Taki K., Shima H. Crit Care Med. 2010 Vol. 38, No. 12 (Suppl.).

Severe Methemoglobinemia Detected by Pulse Oximetry.

Annabi E.H., Barker S,J. Anesth Analg. 2009;108:898–9.

The Measurement of Dyshemoglobins and Total Hemoglobin by Pulse Oximetry.

Barker S.J., Badal J.J. Curr Opin Anaesthesiol. 2008 Dec;21(6):805-10.

The Prevalence of Methemoglobin in HIV Infected Patients on Chronic Dapsone Therapy for Prophylaxis of Pneumocystis jirovecii Infection.

O'Neal H.R. Crit Care Med. 2008 Vol. 36(12) (Suppl):682.

Do Pulse CO-Oximeter Measures of SpMet and SpO2 Correlate with Blood Gas CO-Oximetry in Neonates?

Goldstein M.R., Saesim D., Macknet M., Allard M., Peverini R. Anesthesiology. 2008; 109 A1218.

Benzocaine Induced Methhemoglobin after T.E.E

Macknet M.R., Kimball-Jones P.L. Applegate R.L., Martin R.D., Allard M.W. Respir Care. 2007;52(11).

Rad-57 Rainbow CO-Oximeter in Detecting Methemoglobin during Upper GI Endoscopy - A Case Report

Padakandla U.B. Anesthesiology. 2007; 107: A1543.

Measurement of Carboxyhemoglobin and Methemoglobin by Pulse Oximetry: A Human Volunteer Study.

Barker S.J., Curry J., Redford D., Morgan S. Anesthesiology. 2006 Nov;105(5):892-7.

Noninvasive Monitoring for Methemoglobinemia after Topical Application of Benzocaine during Upper Endoscopy and Trans-esophageal Echocardiography

Schembre D., Ayub K., Gibbons E., Simmons S., Hampson N. Gastroenterol. 126(4) April 2004 Supplement 2. W1284.

Clinical Evidence Key:

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Duplicate abstracts or publications are excluded

This section is intended to provide access to clinical studies conducted using Masimo noninvasive technologies, parameters, and products. We cannot guarantee that all published clinical studies, abstracts and research are listed here. To view individual clinical studies please click on the appropriate tab.

Some uses of the manufacturer’s devices described in the information may not have been approved or cleared by the FDA. See manufacturer labeling for the indications in the product’s cleared indications for use statement.

Clinical evidence is provided to illustrate the performance and accuracy of Masimo technologies. Federal law restricts Masimo devices for medical uses to sale by or on the order of a physician.

Masimo devices with SpHb, SpCO and/or SpMet monitoring are not intended to replace laboratory blood testing. Blood samples should be analyzed by laboratory instruments prior to clinical decision-making.