Brain Function Monitoring

A More Complete Picture Starts with More Complete Data

Brain Function Monitoring helps clinicians monitor the state of the brain under anesthesia with bilateral data acquisition and processing of electroencephalogram (EEG) signals.

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Deliver Anesthesia Based on Individual Patient Need


Identify Incidences of Burst Suppression


Gain a More Complete Picture of Patient Sedation


Why Monitor the Brain During Anesthesia?

The brain is one of the most important organs in the body. By delivering greater insights into changes in brain function under anesthesia, SedLine is designed to help monitor it before, during, and after surgery.

Deliver Balanced Anesthesia

Titrating to the individual patient’s needs may help reduce oversedation,1 which has been linked to poor outcomes2

  • Clinical Evidence

    Clinical benefit of processed electroencephalography (pEEG)

    Patients may experience:

    • Less burst suppression1
    • Less over-sedation1
    • Enhanced recovery and more rapid ventilation weaning3

    Clinicians and hospitals indicate they benefit when technology impacts:

    • Reduced length of stay (LOS)3
    • Reduced cost per patient3
  • Clinical Evidence

    EEG Patterns Associated with PACU Delirium2

    “Conclusions: Specific EEG patterns were associated with PACU delirium. These findings provide valuable information regarding how the brain reacts to surgery and anaesthesia that may lead to strategies to predict PACU delirium and identify key areas of investigation for its prevention.”2

"...reasons why monitoring processed EEG may be of value: prevent awareness, save money by reducing anesthetic cost, prevent excessively deep and unnecessarily deep anesthesia..."

  • Adrian Gelb, MD
    Professor of Anesthesia, UCSF
    Past President of WFSA (World Federation of Societies of Anaesthesiologists)

Clinical Testimonies - The Value of Brain Monitoring in OR and ICU


Debunking Misconceptions About Brain Monitoring

The clinical value of monitoring depth of sedation in the operating room. Featuring Dr. Adrian Gelb (UCSF).


Make Sedation Monitoring a Standard of Care in the ICU

Learn how brain function monitoring in the ICU can support clinicians in making timely, cost-effective care decisions when they matter most. Featuring Dr. Michael Ramsay (Baylor Scott & White).

A More Complete Picture Starts with More Complete Data

See more with SedLine

  1. Four simultaneous channels of frontal EEG waveforms
  2. An enhanced Patient State Index (PSi), a processed EEG parameter related to the effect of anesthetic agents
  3. A Density Spectral Array (DSA) display, which contains left and right spectrograms representing the power of the EEG on both sides of the brain
  4. An optional Multitaper DSA, which may enhance visibility of EEG features

The Power of the Density Spectral Array (DSA)

SedLine offers the flexibility of choosing to display either an enhanced Multitaper Density Spectral Array (DSA) or a standard Hanning DSA.

  • This provides the ability to see the symmetry of left and right sides of the brain.
  • Clearly indicates incidence of burst suppression/isoelectric activity as a black line with blue tip.
  • Spectral edge frequency represents where 95% of the brain power lies.

Understand the DSA

The DSA represents the power of the EEG on both sides of the brain, alongside other patient information provided by SedLine sensors. Watch the video to learn more.


Improved Depth of Sedation Monitoring with Patient State Index (PSi)

SedLine features an enhanced signal processing engine providing a better, more accurate Patient State Index (PSi), a processed EEG parameter related to the effect of anesthetic agents. Learn how we’ve advanced this technology.

  • Enhanced Features

    Parallel Signal Processing Engines

    EMG Graph

    EMG is a common confounding factor that can interfere with EEG signals used in brain function monitoring.4 SedLine uses parallel signal processing engines to extract a clearer EEG signal for computing PSi.

  • Enhanced Features

    Adaptive Signal Processing

    Adaptive Signal Processing Graph

    Power across all frequency bands decreases with age.5 When computing PSi, SedLine uses adaptive signal processing with band-independent features to search for EEG features across many frequency bands.

Total Brain Solution via a Multimodal Platform

Expand visibility in the OR and ICU

Identify changes in brain function and make assessments that may help improve patient outcomes.

O3® Regional Oximetry

Next Generation SedLine can be used simultaneously with O3 Regional Oximetry on the Root platform—delivering a more complete picture of the brain.

  • O3 Regional Oximetry

Root® Patient Monitoring and Connectivity Platform

SedLine connects seamlessly to the Root Patient Monitoring and Connectivity Platform—featuring a customizable, easy-to-interpret display that provides multiple views of brain monitoring data for expanded visibility in the OR and ICU.

  • Root Patient Monitoring and Connectivity Platform

An integrated perioperative monitoring solution on Root

Via Root, SedLine can be used simultaneously with O3 Regional Oximetry, Total Hemoglobin (SpHb®), and the Masimo LiDCO® Hemodynamic Monitoring System.

  • O3 Regional Oximetry
  • Total Hemoglobin (SpHb)
  • Masimo LiDCO Hemodynamic Monitoring System


Click below for links to critical information about SedLine Brain Function Monitoring.


Clinical Cases

Schedule an Evaluation

SedLine is simple and easy to try in your facility and requires minimal additional equipment.


Patient Monitoring and Connectivity Platform

SedLine Module

Connects Patient Cable to Root device

RD SedLine Sensor

Available for Adults and Chilren

Patient Cable

For use with RD SedLine Sensor

Schedule an Evaluation

Try SedLine in your facility today. Contact your Masimo Representative or complete the form below.


  1. Bloom J et al. Anesthesiology Research and Practice. Vol. 2020, pp. 1-6.

  2. Hesse S et al. Br J Anaesth. 2019;122(5):622-634.

  3. Sayed E et al. J Anesth Clin Res.2015;630(6):5. DOI: 10.4172/2155-6148.1000530.

  4. Lobo, Francisco A., and Stefan Schraag. Limitations of anaesthesia depth monitoring. Current Opinion in Anesthesiology. 24, no. 6 (2011): 657-664.

  5. Purdon P et al. Brit J of Anaesth. 10.1093 46-57.

Caution: Federal (USA) law restricts this device to sale by or on the order of a physician. See instructions for use for full prescribing information, including indications, contraindications, warnings, and precautions.